What is the meaning of vexation?

noun

• Anger produced by some annoying irritation.
  • synonyms: annoyance, chafe
• The psychological state of being irritated or annoyed.
  • synonyms: irritation, annoyance, botheration
• Something or someone that causes anxiety; a source of unhappiness.
  • usage: "New York traffic is a constant concern"; "it's a major worry"
  • synonyms: concern, worry, headache
• The act of troubling or annoying someone.
  • synonyms: annoyance, annoying, irritation