| ache(noun, verb, upset, trouble, hurt) |
| throe(noun, verb, state, trouble, feeling) |
| despair(noun, trouble, worry, passion, distress) |
| melancholy(noun, adjective, trouble, worry, passion) |
| depression(noun, trouble, worry, passion, difficulty) |
| rue(noun, verb, state, trouble, feeling) |
| angst(noun, state, feeling, distress, anxiety) |
| agonize(noun, verb, upset, trouble, help) |
| desolation(noun, trouble, worry, passion, distress) |
| unhappiness(noun, trouble, charge, bother, worry) |
| worry(noun, verb, upset, trouble, bother) |
| fret(verb, action, trouble, worry, desire) |
| tribulation(noun, trouble, charge, bother, worry) |
| despondency(noun, trouble, worry, passion, distress) |
| afflict(noun, verb, upset, help, attack) |
| discomfort(noun, verb, upset, trouble, hurt) |
| disquiet(noun, verb, upset, trouble, hurt) |
| dolor(noun, state, trouble, feeling, worry) |
| ail(verb, upset, trouble, hurt, disturb) |
| desperation(noun, worry, distress, anxiety, depression) |