| grimness(noun, dejection) |
| headache(noun, trouble, worry, passion, concern) |
| hopelessness(noun, worry, distress, anxiety, sorrow) |
| inquietude(noun, anxiety, nervousness, restlessness, discontentment) |
| irritate(verb, upset, trouble, disturb, worry) |
| laceration(noun, pain, sickness, ache, anguishes) |
| misfortune(noun, trouble, worry, blow, difficulty) |
| misgiving(noun, worry, concern, anxiety, shame) |
| mournfulness(noun, trouble, worry, pain, sorrow) |
| punish(noun, verb, upset, disturb, strain) |
| remorse(noun, trouble, worry, concern, distress) |
| scourge(noun, verb, help, attack, difficulty) |
| smarting(noun, pain, throbbing) |
| stab(noun, pain, wrench, spasm, twinge) |
| stitch(noun, verb, worry, passion, pain) |
| stress(noun, verb, upset, trouble, charge) |
| struggle(noun, trouble, pain, test, suffering) |
| throes(noun, pain, sickness, torture, ache) |
| tingle(verb, upset, trouble, hurt, disturb) |
| turmoil(noun, anxiety, pain, torment, nervousness) |