| pain(noun, hurt, wrong, harm, difficulty) |
| pestilence(noun, evil, burden, magic, spell) |
| sorrow(noun, trouble, wrong, harm, difficulty) |
| wreck(noun, disorder, ruin, shock, failure) |
| cancer(noun, magic, adversity, spell, affliction) |
| bad news(noun, expression, trouble, ruin, blow) |
| bale(noun, ruin, evil, catastrophe, tragedy) |
| bummer(noun, trouble, defeat, blow, difficulty) |
| comedown(noun, upset, blow, shock, disaster) |
| crisis(noun, action, act, thing, experience) |
| defeat(noun, trouble, hurt, ruin, fall) |
| despair(noun, trouble, ruin, distress, burden) |
| destitution(noun, trouble, hurt, defeat, fall) |
| downer(noun, trouble, defeat, blow, difficulty) |
| grievance(adjective, trouble, difficulty, lack, torment) |
| ill fortune(expression, difficulty, hardship, misfortune, accident) |
| loss(noun, trouble, end, disorder, defeat) |
| ruination(trouble, disorder, ruin, burden, destruction) |
| setback(noun, upset, trouble, ruin, defeat) |
| shock(upset, failure, disaster, catastrophe, surprise) |