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See distal renal tubular acidosis.

... bicarbonate into the distal tubules, which normally secrete hydrogen ions. This disruption impedes the formation of titratable acids and ammonium for excretion and ultimately leads to metabolic acidosis. Treatment is the same as for renal tubular acidosis. In primary proximal RTA the defective reabsorption of bicarbonate is the sole causative factor. In ...

an abnormal condition associated with persistent dehydration, metabolic acidosis, hypokalemia, hyperchloremia, and nephrocalcinosis. It is caused by the kidney's inability to conserve bicarbonate and to adequately acidify the urine. Some forms of RTA are more prevalent in women, older children, and ...