11 entries under cause great distress topic. ×

11
grievously(adverb, painfully, adversely)
8
woefully(adverb, painfully, adversely)
6
distressingly(adverb, painfully)
5
tragically(adverb, adversely)
5
unfortunately(adverb, adversely)
3
lamentably
2
deplorably
1
heartbreakingly
1
heartrendingly
1
regrettably
1
tragical
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APASmart Define. (2015). distressfully thesaurus. Retrieved October 1, 2026, from https://smartdefine.org/distressfully/thesaurus/synonyms
ChicagoSmart Define. 2015. "distressfully thesaurus" https://smartdefine.org/distressfully/thesaurus/synonyms (accessed October 1, 2026).
HarvardSmart Define 2015, distressfully thesaurus, Smart Define, viewed 1 October, 2026, <https://smartdefine.org/distressfully/thesaurus/synonyms>.
MLASmart Define. "distressfully thesaurus" 14 April 2015. Web. 1 October 2026. <https://smartdefine.org/distressfully/thesaurus/synonyms>