| injurious(adjective, awful, terrible, cruel, unkind) |
| intolerable(adjective, tough, severe, harsh, awful) |
| irritated(adjective, hurt, tender, painful, angry) |
| loathsome(adjective, wicked, shocking, dreadful, upsetting) |
| lugubrious(adjective, sad, unhappy, miserable, painful) |
| nagging(adjective, painful, burning, upsetting, irritating) |
| nerve-racking |
| ominous(adjective, hard, severe, offensive, awful) |
| paining(verb, paining) |
| plaintive(adjective, sad, unhappy, sorrow, suffer) |
| pungent |
| rueful(adjective, mean, low, sad, pain) |
| ruthful(adjective, sad, unhappy, sorrow, suffer) |
| sensitive(adjective, hurt, tender, painful, angry) |
| stabbing(adjective, strong, violent) |
| tedious(adjective, sickness, ache, anguishes) |
| tough(adjective, severe, rough, nasty, harsh) |
| troublous(adjective, happy, pain, disturbing) |
| unlucky |
| unsettling(adjective, hard, severe, happy, pain) |