| exasperation(noun, upset, trouble, person, charge) |
| nag(noun, person, bother, distress, pain) |
| torment(noun, trouble, ruin, worry, distress) |
| burden(noun, business, trouble, work, charge) |
| bane(noun, trouble, bother, blow, distress) |
| botheration(noun, trouble, person, bother, strain) |
| hate(noun, trouble, bother, scorn, pain) |
| pain in the neck(noun, expression, idiom, trouble, person) |
| besetment(noun, person, bother, pain, feelings) |
| disturbance(noun, upset, trouble, charge, bother) |
| drip(noun, person, bother, pain, informal) |
| harm(evil, blow, burden, cross, failure) |
| pester(noun, verb, person, pain, irritation) |
| worry(noun, verb, trouble, concern, blow) |
| bind(noun, verb, trouble, bother, worry) |
| disadvantage(noun, trouble, bother, blow, weakness) |
| drawback(noun, trouble, bother, difficulty, weakness) |
| frump(noun, person, pain, mess, irritation) |
| handful |
| harassment(noun, trouble, distress, pain, disturbance) |