| harsh(sharp, powerful, piercing, pungent, stinging) |
| hefty(big, large, grand, huge, major) |
| huge(big, large, grand, major, considerable) |
| indiscriminate(big, large, grand, huge, major) |
| integral(adjective, comprehensive, overall, global, cosmic) |
| integrated(adjective, comprehensive, overall, global, cosmic) |
| intensive |
| invasive |
| large-scale(big, large, grand, huge, major) |
| lengthy(big, large, grand, huge, major) |
| long(big, large, grand, huge, major) |
| major(big, large, grand, huge, considerable) |
| overall(adjective, comprehensive, global, cosmic) |
| overarching(adjective, comprehensive, overall, global, cosmic) |
| overinclusive(adjective, comprehensive, overall, global, cosmic) |
| panoptic(adjective, comprehensive, overall, global, cosmic) |
| protracted(big, large, grand, huge, major) |
| pungent(sharp, harsh, powerful, piercing, stinging) |
| radical |
| rift |