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Etymology: L, de + signare, to mark. Synthetic organic compounds that are designed as analogs of illicit drugs, with the same opioid or other dangerous effects. Because designer drugs are generally not listed as controlled substances by the U.S...

... signatures.(v.t.) That part of a prescription which contains the directions to the patient. It is usually prefaced by S or Sig. (an abbreviation for the Latin signa, imperative of signare to sign or mark).