11 entries under cause great distress topic. ×

9
grievously(adverb, adversely)
9
woefully(adverb, adversely)
7
distressfully(adverb, adversely)
4
heartbreakingly
3
unfortunately(adverb, adversely)
3
deplorably
3
lamentably
2
distressingly
2
heartrendingly
1
regrettably
1
tragical
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APASmart Define. (2015). tragically thesaurus. Retrieved October 1, 2026, from https://smartdefine.org/tragically/thesaurus/synonyms
ChicagoSmart Define. 2015. "tragically thesaurus" https://smartdefine.org/tragically/thesaurus/synonyms (accessed October 1, 2026).
HarvardSmart Define 2015, tragically thesaurus, Smart Define, viewed 1 October, 2026, <https://smartdefine.org/tragically/thesaurus/synonyms>.
MLASmart Define. "tragically thesaurus" 14 April 2015. Web. 1 October 2026. <https://smartdefine.org/tragically/thesaurus/synonyms>