| tough luck(noun, expression, trouble, blow, difficulty) |
| toughness(noun, difficulty, hardness) |
| trickiness(noun, difficulty, complication, complexity, intricacy) |
| undoing(noun, ruin, catastrophe, downfall, tragedy) |
| unfortunateness(noun, luck) |
| unhappiness(noun, trouble, blow, distress, care) |
| untowardness(noun, luck) |
| visitation(noun, trouble, ruin, blow, distress) |
| wearying(noun, difficulty) |
| act of God(noun, expression, idiom, ruin, catastrophe) |
| adverse |
| adverse fate(noun, expression, defeat, blow, distress) |
| adversities |
| afflictions |
| albatross(noun, trouble, force, blow, distress) |
| antagonism(noun, unhelpfulness, unconstructiveness) |
| anxiety(noun, trouble, blow, burden, cross) |
| asperity(noun, trouble, difficulty, lack, torment) |
| austerity(noun, trouble, difficulty, lack, torment) |
| awkwardness(noun, trouble, difficulty, pain, struggle) |