| adversity(noun, trouble, blow, difficulty, distress) |
| affliction(noun, trouble, blow, distress, care) |
| allergy |
| angle |
| bafflement(noun, trouble, worry, anxiety, struggle) |
| blockade(noun, difficulty, hindrance, problem, obstacle) |
| blockage(noun, difficulty, hindrance, problem, obstacle) |
| bottleneck(noun, hindrance) |
| burden(noun, trouble, bother, blow, distress) |
| clog(noun, difficulty, hindrance, problem, obstacle) |
| clutch |
| constipation(noun, hindrance) |
| crimp(noun, difficulty, hindrance, problem) |
| crisis(noun, trouble, worry, difficulty, anxiety) |
| deformity |
| delay(noun, difficulty, hindrance, problem, obstacle) |
| deterrent(noun, difficulty, hindrance, problem, obstacle) |
| disruption(noun, disorder, confusion, mess, muddle) |
| distemper |
| distraction(noun, trouble, question, uncertainty, disturbance) |