| muss(noun, trouble, disorder, difficulty, confusion) |
| opposition(noun, hindrance) |
| ordeal(noun, trouble, bother, blow, difficulty) |
| pathology |
| plight(trouble, disorder, difficulty, mess, puzzle) |
| quagmire(noun, trouble, difficulty, pain, struggle) |
| restriction(noun, difficulty, hindrance, problem) |
| rigor(noun, trouble, blow, distress, care) |
| rigorousness(difficulty, laboriousness, strenuousness) |
| situation(noun, trouble, worry, difficulty, problem) |
| snafu(noun, trouble, disorder, difficulty, confusion) |
| sophistication |
| squeeze(noun, trouble, dispute, difficulty, issue) |
| strait(noun, trouble, worry, difficulty, anxiety) |
| subject(noun, trouble, worry, difficulty, problem) |
| subtlety |
| tight spot |
| topic(noun, trouble, worry, difficulty, problem) |
| topsy-turviness(noun, disorder, confusion, mess, muddle) |
| trickiness(noun, difficulty, adversity, complexity, intricacy) |