| albatross(noun, trouble, bother, blow, distress) |
| calvary(noun, trouble, bother, blow, distress) |
| adversity(noun, trouble, blow, distress, care) |
| affliction(noun, trouble, blow, distress, care) |
| anguish(noun, trouble, bother, blow, distress) |
| annoyance(noun, trouble, bother, blow, distress) |
| bad luck(noun, expression, reverse, trial, suffering) |
| bane(noun, trouble, bother, blow, distress) |
| big problem(noun, expression, trouble, bother, blow) |
| blow(noun, trouble, distress, care, burden) |
| bother(noun, trouble, blow, distress, care) |
| burden(noun, trouble, bother, blow, distress) |
| care(noun, trouble, bother, blow, distress) |
| complication(noun, trouble, bother, blow, distress) |
| crucible(noun, trouble, bother, blow, distress) |
| curse(noun, reverse, trial, suffering, misfortune) |
| difficulty(noun, trouble, blow, distress, care) |
| distress(noun, trouble, blow, care, burden) |
| double whammy(noun, expression, reverse, trial, suffering) |
| drag(noun, trouble, blow, distress, care) |