13
sedative(noun, adjective, medicine, treatment, drug)
11
narcotic(noun, adjective, medicine, treatment, drug)
10
downer(noun, sedative)
6
soporific(noun, adjective)
5
sedative drug(noun, expression, idiom)
5
soothing
4
depressor
4
dreary(adjective, miserable, depressing, cheerless)
4
joyless(adjective, unhappy, miserable, depressing, cheerless)
4
opiate(noun, medicine, treatment, drug, medication)
4
tranquilizer(noun, sedative)
3
bromide
3
calmative
3
cheerless(adjective, miserable, depressing)
3
dismal(adjective, miserable, depressing, cheerless)
3
gloomy(adjective, miserable, depressing, cheerless)
3
pharmaceutical(noun, medicine, treatment, drug, remedy)
3
tranquilizing
2
analgesic
2
anesthetic
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APASmart Define. (2015). depressant thesaurus. Retrieved September 21, 2026, from https://smartdefine.org/depressant/thesaurus/synonyms
ChicagoSmart Define. 2015. "depressant thesaurus" https://smartdefine.org/depressant/thesaurus/synonyms (accessed September 21, 2026).
HarvardSmart Define 2015, depressant thesaurus, Smart Define, viewed 21 September, 2026, <https://smartdefine.org/depressant/thesaurus/synonyms>.
MLASmart Define. "depressant thesaurus" 14 April 2015. Web. 21 September 2026. <https://smartdefine.org/depressant/thesaurus/synonyms>