128 entries under depression topic. ×

43
misery(noun, trouble, ruin, worry, distress)
29
melancholy(noun, trouble, feeling, love, disorder)
26
despondency(noun, trouble, feeling, love, worry)
22
gloom(noun, trouble, worry, passion, distress)
20
dejection(noun, trouble, worry, distress, anxiety)
20
anguish(noun, trouble, worry, passion, distress)
18
desperation(noun, worry, distress, anxiety, sorrow)
17
wretchedness(noun, trouble, worry, passion, distress)
16
discouragement(noun, distress, sorrow, melancholy)
16
grief(noun, feeling, love, worry, passion)
15
distress(noun, verb, upset, trouble, disorder)
14
desolation(noun, trouble, worry, passion, distress)
13
pessimism(noun, belief, doubt, melancholy)
13
woe(noun, trouble, ruin, worry, passion)
13
sorrow(noun, trouble, feeling, love, worry)
11
gloominess(noun, distress, sorrow, doubt)
11
disheartenment(noun, misery, desolation, dejection)
10
sadness(noun, trouble, feeling, love, worry)
8
downheartedness(noun, distress, sorrow, melancholy)
7
agony(noun, trouble, worry, passion, distress)
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APASmart Define. (2016). despair thesaurus. Retrieved September 22, 2026, from https://smartdefine.org/despair/thesaurus/synonyms
ChicagoSmart Define. 2016. "despair thesaurus" https://smartdefine.org/despair/thesaurus/synonyms (accessed September 22, 2026).
HarvardSmart Define 2016, despair thesaurus, Smart Define, viewed 22 September, 2026, <https://smartdefine.org/despair/thesaurus/synonyms>.
MLASmart Define. "despair thesaurus" 23 March 2016. Web. 22 September 2026. <https://smartdefine.org/despair/thesaurus/synonyms>