115 entries under trouble topic. ×

43
misery(noun, ruin, worry, distress)
35
depression(noun, disorder, worry, passion)
29
melancholy(noun, feeling, love, disorder)
26
despondency(noun, feeling, love, worry)
26
heartbreak(noun, worry, distress, pain)
22
gloom(noun, worry, passion, distress)
20
dejection(noun, worry, distress, anxiety)
20
anguish(noun, worry, passion, distress)
17
wretchedness(noun, worry, passion, distress)
15
distress(noun, verb, upset, disorder)
14
desolation(noun, worry, passion, distress)
13
woe(noun, ruin, worry, passion)
13
sorrow(noun, feeling, love, worry)
10
sadness(noun, feeling, love, worry)
7
agony(noun, worry, passion, distress)
7
pain(noun, disorder, worry, passion)
7
tribulation(noun, worry, distress, pain)
7
unhappiness(noun, worry, passion, distress)
6
heartache(noun, worry, passion, distress)
6
worry(noun, verb, passion, distress)
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APASmart Define. (2016). despair thesaurus. Retrieved September 23, 2026, from https://smartdefine.org/despair/thesaurus/synonyms
ChicagoSmart Define. 2016. "despair thesaurus" https://smartdefine.org/despair/thesaurus/synonyms (accessed September 23, 2026).
HarvardSmart Define 2016, despair thesaurus, Smart Define, viewed 23 September, 2026, <https://smartdefine.org/despair/thesaurus/synonyms>.
MLASmart Define. "despair thesaurus" 23 March 2016. Web. 23 September 2026. <https://smartdefine.org/despair/thesaurus/synonyms>