| acrimony(noun, hurt, passion, rise, temper) |
| adversity(noun, trouble, blow, distress, care) |
| aggro(noun, trouble, difficulty, stress, annoyance) |
| angst(noun, pain, sorrow, misery, suffering) |
| antipathy(noun, dislike, anger, hatred, bitterness) |
| bane(noun, trouble, bother, blow, distress) |
| bedevilment(noun, annoyance, nuisance, aggravation, pestering) |
| besetment(noun, bother, pain, feelings, annoyance) |
| bind(noun, bother, worry, distress, anxiety) |
| boredom(noun, worry, anxiety, disappointment, unhappiness) |
| bothering(noun, act, pain, feelings, disturbance) |
| bruise(noun, pain) |
| bugbear(noun, gripe) |
| bummer(hindrance, disappointment, annoyance, prevention, blocking) |
| burn(noun, distress, pain, tenderness, agony) |
| caustic(adjective, physical energy) |
| cheerlessness(noun, discontentment) |
| commotion(noun, trouble, bother, worry, distress) |
| cramp(noun, distress, pain, tenderness, agony) |
| crick(noun, distress, pain, tenderness, agony) |