What is the meaning of sore?

noun

• An open skin infection.

adjective

• Hurting.
  • usage: "the tender spot on his jaw"
  • synonyms: sensitive, raw, tender
• Causing misery or pain or distress.
  • usage: "it was a sore trial to him"; "the painful process of growing up"
  • synonyms: afflictive, painful
• Roused to anger.
  • usage: "stayed huffy a good while- Mark Twain; "she gets mad when you wake her up so early"; "mad at his friend"; "sore over a remark"
  • synonyms: huffy, mad