144 entries under difficulty topic. ×

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bump(noun, restraint, hindrance, problem)
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case(trouble, lack, torment, adversity)
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catch(hindrance, problem, impediment, discouragement)
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check(hindrance, problem, impediment, discouragement)
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choke point(noun, expression, predicament, crisis)
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clog(hindrance, problem, impediment, discouragement)
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crimp(hindrance, problem, impediment, discouragement)
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discomfort(trouble, lack, torment, adversity)
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disincentive(noun, restraint, hindrance, problem)
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drudgery(trouble, lack, torment, adversity)
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encumbrance(hindrance, problem, impediment, discouragement)
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fatigue(trouble, lack, torment, adversity)
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hamper(noun, restraint, hindrance, problem)
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handicap(hindrance, problem, impediment, discouragement)
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hazard(trouble, lack, torment, adversity)
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hindrance(problem, impediment, discouragement)
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hitch(hindrance, problem, impediment, discouragement)
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hurdle(noun, restraint, hindrance, problem)
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impediment(hindrance, problem, discouragement)
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injury(trouble, lack, torment, adversity)
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APASmart Define. (2015). vicissitude thesaurus. Retrieved September 25, 2026, from https://smartdefine.org/vicissitude/thesaurus/synonyms
ChicagoSmart Define. 2015. "vicissitude thesaurus" https://smartdefine.org/vicissitude/thesaurus/synonyms (accessed September 25, 2026).
HarvardSmart Define 2015, vicissitude thesaurus, Smart Define, viewed 25 September, 2026, <https://smartdefine.org/vicissitude/thesaurus/synonyms>.
MLASmart Define. "vicissitude thesaurus" 10 April 2015. Web. 25 September 2026. <https://smartdefine.org/vicissitude/thesaurus/synonyms>