4
blow(noun, upset, trouble, hurt, ruin)
4
concern(noun, trouble, worry, strain, difficulty)
4
defect(noun, upset, disorder, weakness, condition)
4
desolation(noun, trouble, ruin, worry, distress)
4
discomfort(noun, trouble, hurt, worry, concern)
4
distemper(noun, disorder, disturbance, defect, sickness)
4
infection(noun, disorder, disease, condition, cold)
4
misadventure(noun, upset, trouble, ruin, blow)
4
nemesis(noun, opponent, bane, archenemy)
4
pressure(noun, charge, worry, strain, difficulty)
4
retribution(noun, curse, punishment, fate, doom)
4
reverse(noun, upset, trouble, hurt, ruin)
4
rigor(noun, trouble, blow, distress, care)
4
sadness(noun, trouble, worry, distress, care)
4
smart(noun, distress, pain, tenderness, agony)
4
smarting(noun, hurt, distress, pain, tenderness)
4
stress(noun, trouble, force, charge, worry)
4
throe(noun, trouble, hurt, distress, care)
4
undoing(trouble, ruin, burden, misery, catastrophe)
4
worry(noun, trouble, concern, blow, strain)
10 years ago|24k views|share |citing 
APASmart Define. (2016). affliction thesaurus. Retrieved September 22, 2026, from https://smartdefine.org/affliction/thesaurus/synonyms
ChicagoSmart Define. 2016. "affliction thesaurus" https://smartdefine.org/affliction/thesaurus/synonyms (accessed September 22, 2026).
HarvardSmart Define 2016, affliction thesaurus, Smart Define, viewed 22 September, 2026, <https://smartdefine.org/affliction/thesaurus/synonyms>.
MLASmart Define. "affliction thesaurus" 29 February 2016. Web. 22 September 2026. <https://smartdefine.org/affliction/thesaurus/synonyms>