11
spiritual apathy
11
disheartenment(noun, depression, misery, desolation, dejection)
10
sadness(noun, trouble, feeling, love, worry)
10
fear(noun, worry, distress, anxiety, melancholy)
8
dispiritedness(noun, distress, sorrow, sadness, gloom)
8
downheartedness(noun, distress, sorrow, depression, melancholy)
8
give up(verb, expression, phrasal verb, surrender, submit)
7
agony(noun, trouble, worry, passion, distress)
7
lose hope(verb, expression, idiom, drop, abandon)
7
pain(noun, trouble, disorder, worry, passion)
7
surrender(noun, verb, stop, drop, give)
7
tribulation(noun, trouble, worry, distress, pain)
7
unhappiness(noun, trouble, worry, passion, distress)
7
yield(verb, stop, drop, give, abandon)
6
blues(noun, worry, passion, distress, pain)
6
disconsolateness(noun, worry, distress, anxiety, depression)
6
forlornness(noun, depression, misery, desolation, hopelessness)
6
heartache(noun, trouble, worry, passion, distress)
6
lose heart(verb, expression, idiom, drop, give)
6
mope(verb, melancholy, sadness, dejection, languish)
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APASmart Define. (2016). despair thesaurus. Retrieved September 21, 2026, from https://smartdefine.org/despair/thesaurus/synonyms
ChicagoSmart Define. 2016. "despair thesaurus" https://smartdefine.org/despair/thesaurus/synonyms (accessed September 21, 2026).
HarvardSmart Define 2016, despair thesaurus, Smart Define, viewed 21 September, 2026, <https://smartdefine.org/despair/thesaurus/synonyms>.
MLASmart Define. "despair thesaurus" 23 March 2016. Web. 21 September 2026. <https://smartdefine.org/despair/thesaurus/synonyms>