| smarting(noun, pain, throbbing) |
| soreness(noun, pain, sickness, ache, anguishes) |
| splitting headache(noun, expression, migraine) |
| tribulation(noun, trouble, distress, care, pain) |
| affliction(noun, trouble, distress, care, pain) |
| annoying |
| backache(noun, pain, throbbing) |
| bellyache(trouble, strain, difficulty, problem, aggravation) |
| besetment(bother, pain, irritation, annoyance, nuisance) |
| blight(bother, annoyance, nuisance) |
| business(noun, work, burden, job, exercise) |
| care(noun, trouble, concern, strain, difficulty) |
| chafe |
| charge(noun, business, work, burden, job) |
| chore(noun, job, duty, commission, mission) |
| crashing bore(expression, bother, annoyance, nuisance) |
| dilemma(noun, trouble, dispute, difficulty, pain) |
| downer(noun, bother, distress, reverse, trial) |
| flat tire(noun, expression, bother, drag, nuisance) |
| fret |