| torture(noun, trouble, worry, passion, concern) |
| trial(noun, trouble, bother, concern, strain) |
| twinge(noun, trouble, worry, passion, care) |
| ado(trouble, strain, difficulty, problem, aggravation) |
| amyotrophic lateral sclerosis(expression, idiom) |
| anxiety(noun, trouble, concern, strain, difficulty) |
| bad news(noun, expression, trouble, worry, passion) |
| drip(noun, bother, pain, irritation, annoyance) |
| exasperation(noun, trouble, bother, strain, difficulty) |
| fear(noun, concern, anxiety, apprehension) |
| heartache(noun, trouble, worry, passion, concern) |
| heartburn |
| hurt(noun, pain, physical pain, throbbing) |
| irritant(noun, trouble, bother, strain, difficulty) |
| malaise(noun, trouble, care, pain, cross) |
| onus(noun, business, work, burden, heavy) |
| pain in the neck(noun, expression, idiom, trouble, bother) |
| peck of troubles(expression, idiom) |
| province(noun, business, work, burden, job) |
| sea of troubles(expression, idiom) |