| bitterness(noun, worry, concern, distress, pain) |
| regret(noun, action, trouble, worry, distress) |
| heartsickness(noun, pain, sorrow, woe, misery) |
| dolefulness(noun, pain, sorrow, depression, melancholy) |
| misfortune(noun, trouble, worry, blow, distress) |
| rue(noun, trouble, worry, distress, pain) |
| tribulation(noun, trouble, bother, worry, blow) |
| bale(noun, pain, sorrow, misery, suffering) |
| bereavement(noun, trouble, worry, pain, sorrow) |
| calamity(noun, distress, sadness, disaster, catastrophe) |
| depression(noun, trouble, worry, distress, pain) |
| despondency(noun, trouble, worry, distress, pain) |
| emotional misery(noun, expression, pain, misery, suffering) |
| mental misery(noun, expression, pain, misery, suffering) |
| sadness(noun, trouble, worry, distress, care) |
| throe(noun, trouble, care, pain, shame) |
| ache(noun, trouble, care, pain, shame) |
| contretemps(disaster, catastrophe, calamity) |
| disaster(noun, distress, sadness, catastrophe, anguish) |
| infelicity(noun, trouble, worry, pain, sorrow) |