| worriment(noun, trouble, care, pain, shame) |
| dejection(noun, trouble, worry, distress, care) |
| misadventure(noun, distress, sadness, disaster, catastrophe) |
| ordeal(noun, trouble, bother, blow, distress) |
| plague(noun, trouble, bother, blow, distress) |
| aching heart(noun, expression, pain, misery, suffering) |
| catastrophe(noun, distress, sadness, disaster, unhappiness) |
| bane(noun, trouble, bother, blow, distress) |
| hardship(noun, trouble, worry, blow, distress) |
| tragedy(noun, distress, sadness, disaster, catastrophe) |
| wretchedness(noun, trouble, bother, worry, blow) |
| adversity(noun, trouble, blow, distress, care) |
| agony of mind(noun, expression, pain, misery, suffering) |
| angst(noun, pain, sorrow, torment, misery) |
| blue devils(noun, expression, pain, sorrow, depression) |
| blue funk(noun, expression, pain, sorrow, depression) |
| bother(noun, trouble, blow, distress, care) |
| burden(noun, trouble, bother, blow, distress) |
| crucible(noun, trouble, bother, blow, distress) |
| dysphoria(noun, pain, sorrow, depression, melancholy) |