| agonize |
| agonizingness |
| albatross(noun, trouble, bother, blow, distress) |
| annoyance(noun, trouble, bother, worry, concern) |
| anxiety(noun, trouble, care, pain, cross) |
| apology(noun, worry, concern, shame, anguish) |
| bad news(noun, expression, trouble, worry, distress) |
| bemoaning(noun, trouble, worry, distress, pain) |
| big problem(noun, expression, trouble, bother, blow) |
| blow(noun, trouble, worry, distress, care) |
| calvary(noun, trouble, bother, blow, distress) |
| complication(noun, trouble, bother, blow, distress) |
| compunction(noun, worry, concern, shame, woe) |
| conscience(noun, worry, concern, shame, anguish) |
| contrition(noun, worry, concern, shame, woe) |
| cross to bear(noun, expression, idiom, trouble, bother) |
| demur(noun, worry, concern, shame, anguish) |
| depress |
| discomfort(noun, trouble, worry, concern, care) |
| dissatisfaction(noun, worry, concern, shame, anguish) |