| agony(noun, trouble, worry, distress, care) |
| catastrophe(noun, distress, pain, collapse, depression) |
| wretchedness(noun, trouble, bother, worry, blow) |
| torture(noun, trouble, worry, care, pain) |
| visitation(noun, state, trouble, bother, easy) |
| burden(noun, trouble, charge, hard, bother) |
| heartache(noun, trouble, worry, concern, distress) |
| cross(noun, trouble, hard, blow, difficulty) |
| scourge(noun, difficulty, burden, collapse, woe) |
| travail(noun, worry, struggle, sorrow, want) |
| worry(noun, trouble, blow, distress, anxiety) |
| bad luck(noun, expression, pain, trial, unhappiness) |
| bane(noun, trouble, bother, blow, distress) |
| blight(noun, adversity) |
| bummer(noun, distress, pain, sorrow, depression) |
| care(noun, trouble, bother, worry, concern) |
| crucible(noun, state, trouble, bother, easy) |
| despair(noun, trouble, worry, distress, pain) |
| downer(noun, distress, pain, sorrow, depression) |
| evil(noun, adjective, trouble, harm, immorality) |