| heartbreak(noun, trouble, bother, worry, blow) |
| plague(noun, trouble, bother, blow, difficulty) |
| tragedy(noun, trouble, blow, distress, cross) |
| bad fortune(noun, pain, bad feelings, sufferings) |
| excruciation(noun, sickness, ache, anguishes) |
| infelicity(noun, trouble, worry, blow, burden) |
| mischance(noun, trouble, pain, collapse, scourge) |
| oppression(noun, charge, worry, strain, distress) |
| persecution(noun, trouble, worry, difficulty, pain) |
| rigor(noun, trouble, blow, distress, care) |
| sadness(noun, trouble, worry, distress, care) |
| struggle(noun, trouble, worry, difficulty, distress) |
| test(noun, trouble, torment, trial, suffering) |
| unhappiness(noun, trouble, charge, bother, worry) |
| annoyance(noun, trouble, charge, bother, worry) |
| bad news(noun, expression, trouble, worry, blow) |
| chore(noun, routine, bore, task, inconvenience) |
| desolation(noun, trouble, worry, care, pain) |
| disquiet(noun, trouble, worry, concern, distress) |
| dolor(noun, trouble, worry, distress, care) |