| perplexing(adjective, hard, fancy, difficult, complex) |
| prickly(burning, thorny, stinging, spiky, spiny) |
| problematic(adjective, hard, tough, fancy, severe) |
| sharp(adjective, sickness, ache, anguishes) |
| terrible(adjective, severe, difficult, tender, unpleasant) |
| unfavorable(adjective, bad, unpleasant, negative, adverse) |
| wretched(verb, adjective, person, rough, unpleasant) |
| alarming(adjective, hard, severe, offensive, irritating) |
| burning(adjective, sickness, ache, anguishes) |
| contrary(adjective, difficult, unpleasant, negative, critical) |
| crushing(adjective, severe, difficult, harsh, heavy) |
| cumbersome(adjective, difficult) |
| dangerous(adjective, hard, severe, evil, rough) |
| detrimental(adjective, adverse, damaging, disparaging, hurtful) |
| dire(adjective, sickness, ache, anguishes) |
| embarrassing(adjective, hard, severe, offensive, awkward) |
| extreme(adjective, sickness, ache, anguishes) |
| hurting(adjective, sickness, ache, anguishes) |
| inflamed(adjective, sickness, ache, anguishes) |
| infuriating(adjective, aggravating) |