23
misfortune(noun, trouble, strike, distress, issue)
13
difficulty(noun, trouble, strike, issue, hardship)
11
tragedy(noun, difficulty, problem, misfortune, drama)
9
adversity(noun, trouble, difficulty, woe, problem)
7
impossibility(noun, case, situation, circumstances)
6
disadvantage(noun, negative, problem, lack of)
6
failure(noun, difficulty, problem, misfortune)
6
mischance(noun, negative, problem, lack of)
5
catastrophe(noun, difficulty, problem, hardship, misfortune)
5
reverse(noun, difficulty, problem, hardship, misfortune)
4
disaster(noun, difficulty, problem, hardship, misfortune)
4
threat(noun, business, danger, denunciation)
4
accident(noun, difficulty, problem, hardship, misfortune)
4
mishap(noun, difficulty, problem, hardship, misfortune)
4
setback(noun, trouble, difficulty, woe, problem)
4
misadventure(noun, difficulty, problem, hardship, misfortune)
4
trap(noun, trouble, distress, woe)
3
calamity(noun, difficulty, problem, hardship, misfortune)
3
hitch(noun, trouble, help, difficulty, woe)
3
buffeting(noun, hardship, worries, anxieties)
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APASmart Define. (2016). opportunity thesaurus. Retrieved September 26, 2026, from https://smartdefine.org/opportunity/thesaurus/antonyms
ChicagoSmart Define. 2016. "opportunity thesaurus" https://smartdefine.org/opportunity/thesaurus/antonyms (accessed September 26, 2026).
HarvardSmart Define 2016, opportunity thesaurus, Smart Define, viewed 26 September, 2026, <https://smartdefine.org/opportunity/thesaurus/antonyms>.
MLASmart Define. "opportunity thesaurus" 25 February 2016. Web. 26 September 2026. <https://smartdefine.org/opportunity/thesaurus/antonyms>